Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002703 | 1.00 | EGFR (0.56) | EGFRBTKINSRALK | |
| SCHEMBL25001815 | 0.92 | EGFR (0.46) | EGFRBTKINSRALK | |
| SCHEMBL25002390 | 0.88 | EGFR (0.64) | EGFR | |
| SCHEMBL25001890 | 0.82 | EGFR (0.55) | EGFRBTK | |
| SCHEMBL25001527 | 0.82 | EGFR (0.55) | EGFRBTKINSRALK | |
| SCHEMBL25002978 | 0.82 | EGFR (0.48) | EGFR | |
| SCHEMBL23442652 | 0.82 | EGFR (0.66) | EGFRBTKINSRALK | |
| SCHEMBL25001604 | 0.82 | EGFR (0.43) | EGFRBTKINSRALK | |
| SCHEMBL25001639 | 0.82 | EGFR (0.48) | EGFR | |
| SCHEMBL30748527 | 0.82 | EGFR (0.48) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |