Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.37 |
| ▸ | TTK | P33981 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31373559 | 0.80 | SCN10A (0.39) | GSK3AGSK3BFFAR2SIGMAR1SCN10A | |
| SCHEMBL26650908 | 0.80 | SCN10A (0.39) | GSK3AGSK3BFFAR2SIGMAR1SCN10A | |
| SCHEMBL30600701 | 0.79 | GRM4 (0.52) | GRM4GRIA1PDE10AFFAR2MTOR | |
| SCHEMBL30748602 | 0.78 | GRM4 (0.44) | GRM4GSK3AGSK3BGRIA1PDE10A | |
| SCHEMBL29575286 | 0.77 | PRKD1 (0.42) | GSK3AGSK3BPDE10ATTKPIK3CA | |
| SCHEMBL24394248 | 0.75 | TTK (0.39) | GRM4GRIA1PDE10ATTKPIK3CA | |
| SCHEMBL26942890 | 0.73 | TTK (0.42) | GRM4FFAR2TTKSCN10A | |
| SCHEMBL29575713 | 0.72 | NEK2 (0.53) | — | |
| SCHEMBL16711029 | 0.72 | CYP3A4 (0.41) | GSK3AGSK3BFFAR2SIGMAR1PIK3CA | |
| SCHEMBL31219663 | 0.70 | GRM4 (0.43) | GRM4GSK3AGRIA1PDE10ATTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |