Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SORD | Q00796 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748617 | 0.80 | GSK3A (0.39) | GRM4GSK3BGSK3ACNR2MAOB | |
| SCHEMBL26650593 | 0.80 | GSK3A (0.39) | GRM4GSK3BGSK3ACNR2MAOB | |
| SCHEMBL3690677 | 0.78 | HTR2C (0.69) | HTR2C | |
| SCHEMBL30748580 | 0.78 | GRM4 (0.41) | GRM4GSK3BGSK3AGRIA1PDE10A | |
| SCHEMBL31219663 | 0.77 | GRM4 (0.43) | GRM4HRH4HTR2CGSK3AGRIA1 | |
| SCHEMBL26650750 | 0.75 | GSK3A (0.43) | GSK3BGSK3ACNR2 | |
| SCHEMBL31373518 | 0.75 | GSK3A (0.43) | GSK3BGSK3ACNR2 | |
| SCHEMBL30600701 | 0.74 | GRM4 (0.52) | GRM4HRH4HTR2CGRIA1PDE10A | |
| SCHEMBL17583291 | 0.71 | SCN10A (0.40) | GRM4GSK3BGSK3AGRIA1PDE10A | |
| SCHEMBL12327159 | 0.71 | PIM1 (0.43) | GRM4GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |