Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | WHR1 | P49842 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748617 | 1.00 | GSK3A (0.39) | GSK3AGSK3BKDM4EPOLBHTT | |
| SCHEMBL31373518 | 0.81 | GSK3A (0.43) | GSK3AGSK3BKDM4EHTTWHR1 | |
| SCHEMBL26650750 | 0.81 | GSK3A (0.43) | GSK3AGSK3BKDM4EHTTWHR1 | |
| SCHEMBL30748602 | 0.80 | GRM4 (0.44) | GSK3AGSK3BGRM4MAOBCNR2 | |
| SCHEMBL31373516 | 0.74 | ELANE (0.39) | GSK3AGSK3BWHR1PRMT3CNR2 | |
| SCHEMBL26650961 | 0.74 | ELANE (0.39) | GSK3AGSK3BWHR1PRMT3CNR2 | |
| SCHEMBL26650487 | 0.73 | GRM4 (0.43) | GRM4NOS3NOS1NOS2PIK3CA | |
| SCHEMBL31299059 | 0.71 | NOS3 (0.37) | NOS3NOS1NOS2PIK3CAMTOR | |
| SCHEMBL30748646 | 0.70 | NOS3 (0.36) | GRM4NOS3NOS1NOS2MAOB | |
| SCHEMBL26650968 | 0.70 | NOS3 (0.36) | GRM4NOS3NOS1NOS2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |