SCHEMBL30748808

SCHEMBL30748808

CCCC[Si](C)(C)OCc1ncc2c(n1)N(c1ccc(OC3CCOCC3)cc1)CC21CC1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AXL P30530 1/20 0.31
TYRO3 Q06418 1/20 0.31
MERTK Q12866 1/20 0.31
TRPV4 Q9HBA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691272 0.86 PDE1A (0.31) AXLTYRO3MERTK
SCHEMBL30749066 0.82 CHRM4 (0.34) AXLTYRO3MERTKTRPV4
SCHEMBL31691440 0.78 PTPN11 (0.34) TRPV4
SCHEMBL31691212 0.77 PDE4B (0.37)
SCHEMBL31691262 0.76 PDE10A (0.31)
SCHEMBL30749012 0.73 PDE4B (0.40)
SCHEMBL30748796 0.72 CHRM4 (0.33)
SCHEMBL30748910 0.69 PDE4B (0.34)
SCHEMBL30749019 0.68 PDE4B (0.40)
SCHEMBL31691240 0.66 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed