SCHEMBL30748796

SCHEMBL30748796

OCc1ncc2c(n1)N(c1ccc(OC3CCOCC3)nc1)CC21CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM4 P08173 1/20 0.33
P2RX3 P56373 2/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30749066 0.89 CHRM4 (0.34) CHRM4P2RX3PIK3CDPIK3CA
SCHEMBL31691262 0.85 PDE10A (0.31)
SCHEMBL30749012 0.84 PDE4B (0.40) CHRM4PIK3CD
SCHEMBL30748909 0.80 ACACB (0.37) CHRM4P2RX3
SCHEMBL30749034 0.79 ALDH1A1 (0.45) PIK3CA
SCHEMBL31691272 0.74 PDE1A (0.31)
SCHEMBL31691440 0.73 PTPN11 (0.34) P2RX3PIK3CA
SCHEMBL30748954 0.72 CDK2 (0.37) CHRM4
SCHEMBL30748881 0.71 PIK3CA (0.38) CHRM4PIK3CDPIK3CA
SCHEMBL30749098 0.70 CCNE1 (0.36) CHRM4P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT CHRM4 4607/4885P2RX3 1730/4885PIK3CD 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.