Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748759 | 1.00 | MAPT (0.42) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL8997506 | 0.84 | MAPT (0.44) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL20745730 | 0.77 | MAPT (0.64) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL20745929 | 0.77 | MAPT (0.64) | MAPTPDK1PDK2PDK3PDK4 | |
| SCHEMBL29030905 | 0.75 | GBA1 (0.46) | LMNA | |
| SCHEMBL20745635 | 0.74 | MAPT (0.42) | MAPTMAOAMAOB | |
| SCHEMBL20745376 | 0.74 | HDAC11 (0.46) | MAPTLMNA | |
| SCHEMBL16765922 | 0.74 | HDAC11 (0.46) | MAPTLMNA | |
| SCHEMBL20745637 | 0.74 | MAPT (0.42) | MAPTMAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL27989210 | 0.74 | CA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |