Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 5/20 | 0.49 |
| ▸ | JAK1 | P23458 | 5/20 | 0.49 |
| ▸ | PAK4 | O96013 | 3/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 4/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749089 | 0.86 | HPGDS (0.56) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL17731711 | 0.80 | HPGDS (0.58) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8366783 | 0.78 | ADORA1 (0.79) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL22975471 | 0.78 | HPGDS (0.60) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL1018595 | 0.78 | HPGDS (0.56) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL30748993 | 0.77 | HPGDS (0.55) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL11837002 | 0.77 | HPGDS (0.55) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL11832349 | 0.75 | HPGDS (0.56) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL11876464 | 0.75 | HPGDS (0.56) | HPGDSADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL17089408 | 0.75 | HPGDS (0.52) | HPGDSADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | VHL, BRCA1, TERT | HPGDS 168/4885ADORA1 3025/4885ADORA3 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.