Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748941 | 0.87 | SCN9A (0.54) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| SCHEMBL30748981 | 0.80 | SCN9A (0.58) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| SCHEMBL30748817 | 0.76 | SCN9A (0.54) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| SCHEMBL30046349 | 0.75 | SCN9A (0.76) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| SCHEMBL690620 | 0.73 | SCN9A (0.51) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| SCHEMBL1008870 | 0.71 | MAPT (0.70) | SCN9ASCN5AKCNH2RAB9AMAPT | |
| SCHEMBL13963107 | 0.71 | CYP1A2 (0.75) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| SCHEMBL691636 | 0.71 | SCN9A (0.48) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL4519585 | 0.70 | CYP1A2 (0.73) | SCN9ASCN5AKCNH2RAB9AMEN1 | |
| SCHEMBL13335945 | 0.70 | RAB9A (0.59) | SCN9AKCNH2RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | VHL, BRCA1, TERT | SCN9A 4230/4885SCN5A 4428/4885KCNH2 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.