Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117681 | 0.85 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL31612903 | 0.85 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL1835614 | 0.85 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL6017672 | 0.82 | GBA2 (0.39) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL31612922 | 0.81 | LMNA (0.43) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL13390099 | 0.81 | HTR2C (0.31) | — | |
| SCHEMBL27844684 | 0.80 | MMP2 (0.46) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL14918089 | 0.80 | MMP2 (0.46) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL7788793 | 0.79 | GBA2 (0.51) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL30118071 | 0.78 | LMNA (0.43) | LMNASMN1; SMN2POLBGBA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |