SCHEMBL30749042

SCHEMBL30749042

CNc1ncnc2c1C(C)(C)C(=O)N2c1ccc(OC2CCCCC2)nc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACACB O00763 4/20 0.38
AR P10275 5/20 0.36
HRH3 Q9Y5N1 6/20 0.35
FLT3 P36888 2/20 0.34
BTK Q06187 2/20 0.33
LCAT P04180 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748741 0.87 ACACB (0.35) ACACBHRH3KCNH2
SCHEMBL30749116 0.86 ACACB (0.37) ACACBARHRH3FLT3BTK
SCHEMBL30748989 0.84 ACACB (0.39) ACACBARHRH3FLT3BTK
SCHEMBL31691343 0.80 ACACB (0.34) ACACBARLCAT
SCHEMBL30748997 0.79 ACACB (0.37) ACACBARHRH3BTKLCAT
SCHEMBL30748804 0.76 ACACB (0.38) ACACBARHRH3FLT3BTK
SCHEMBL30748874 0.75 CHRM4 (0.45) ACACBARHRH3BTKLCAT
SCHEMBL30749083 0.73 ACACB (0.38) ACACBHRH3KCNH2
SCHEMBL30748722 0.71 TTBK1 (0.38)
SCHEMBL30748831 0.70 HRH3 (0.36) ACACBHRH3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed