Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748857 | 0.87 | HRH3 (0.39) | GRM2HRH3KCNH2ELANEHPGD | |
| SCHEMBL30749116 | 0.87 | ACACB (0.37) | ACACBHRH3KCNH2SCN5ASCN9A | |
| SCHEMBL30748741 | 0.85 | ACACB (0.35) | ACACBHRH3KCNH2HPGD | |
| SCHEMBL30748912 | 0.77 | GRM2 (0.34) | GRM2HRH3KCNH2 | |
| SCHEMBL30748997 | 0.75 | ACACB (0.37) | ACACBHRH3KCNH2 | |
| SCHEMBL30749100 | 0.74 | PRKDC (0.42) | ELANEALDH1A1MEN1KMT2A | |
| SCHEMBL30749042 | 0.73 | ACACB (0.38) | ACACBHRH3KCNH2 | |
| SCHEMBL30748831 | 0.72 | HRH3 (0.36) | ACACBHRH3KCNH2ALDH1A1 | |
| SCHEMBL30748874 | 0.71 | CHRM4 (0.45) | ACACBHRH3SCN5ASCN9A | |
| SCHEMBL30749132 | 0.68 | RAB9A (0.41) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |