SCHEMBL30748722

SCHEMBL30748722

CNc1ncnc2c1C(C)(C)C(=O)N2c1ccc(N2CCOCC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTBK1 Q5TCY1 2/20 0.38
TTBK2 Q6IQ55 2/20 0.38
PRKDC P78527 3/20 0.38
MAPT P10636 7/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
HTT P42858 3/20 0.37
MAPK1 P28482 1/20 0.37
AHR P35869 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LRRK2 Q5S007 1/20 0.37
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
DGAT1 O75907 1/20 0.36
JAK3 P52333 1/20 0.36
PTK2 Q05397 1/20 0.34
KDM4E B2RXH2 3/20 0.34
HPGD P15428 2/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748915 0.88 ADORA3 (0.40) TTBK1TTBK2PRKDCMAPTRAB9A
SCHEMBL30749100 0.84 PRKDC (0.42) PRKDCMAPTRAB9AALDH1A1SMN1; SMN2
SCHEMBL30748787 0.80 L3MBTL1 (0.36) MAPTRAB9APOLBHTTMAPK1
SCHEMBL30748741 0.75 ACACB (0.35) HPGD
SCHEMBL31691354 0.74 AGXT (0.33) MAPTHTTMAPK1L3MBTL1LRRK2
SCHEMBL30748933 0.72 SYK (0.40) MAPTMAPK1L3MBTL1LRRK2ALDH1A1
SCHEMBL30749038 0.72 ADORA3 (0.39) MAPTRAB9ANPC1POLBHTT
SCHEMBL30749042 0.71 ACACB (0.38)
SCHEMBL30748952 0.70 SYK (0.37) MAPTRAB9ANPC1POLBL3MBTL1
SCHEMBL30748754 0.69 XDH (0.36) MAPTHTTMAPK1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed