SCHEMBL30749068

SCHEMBL30749068

CC(C)Oc1ccc(N2C(=O)C3(CC3)c3cnc(CO)nc32)cn1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 4/20 0.40
CCNE1 P24864 5/20 0.35
CDK2 P24941 5/20 0.35
MARK3 P27448 1/20 0.35
ACACB O00763 2/20 0.34
PTGDR Q13258 1/20 0.33
TRPV3 Q8NET8 1/20 0.32
LCAT P04180 2/20 0.32
S1PR1 P21453 1/20 0.32
P2RX3 P56373 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748962 0.85 LIPE (0.38) LIPECCNE1CDK2MARK3ACACB
SCHEMBL30748954 0.84 CDK2 (0.37) CCNE1CDK2ACACB
SCHEMBL30749098 0.82 CCNE1 (0.36) CCNE1CDK2ACACBLCATP2RX3
SCHEMBL30748908 0.82 ACACB (0.37) CCNE1CDK2ACACBLCATP2RX3
SCHEMBL30749047 0.78 CCNE1 (0.38) CCNE1CDK2MARK3ALDH1A1
SCHEMBL30749006 0.76 EGLN1 (0.44) CCNE1CDK2MARK3ALDH1A1
SCHEMBL30748793 0.76 CDK2 (0.37) CCNE1CDK2
SCHEMBL30748774 0.75 HTT (0.40) CCNE1CDK2ALDH1A1
SCHEMBL30748888 0.75 CCNE1 (0.39) CCNE1CDK2ALDH1A1
SCHEMBL30749138 0.73 CDK2 (0.40) CCNE1CDK2MARK3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT LIPE 983/4885CCNE1 2310/4885CDK2 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.