Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 17/20 | 0.54 |
| ▸ | TPO | P07202 | 15/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224199 | 0.89 | MPO (0.56) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL27223609 | 0.89 | MPO (0.56) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL27223595 | 0.88 | MPO (0.51) | MPOTPOKCNH2CYP3A4MEN1 | |
| SCHEMBL30749376 | 0.88 | MPO (0.51) | MPOTPOKCNH2CYP3A4MEN1 | |
| SCHEMBL30749315 | 0.86 | MPO (0.53) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30749342 | 0.84 | MPO (0.53) | MPOTPOKCNH2CYP3A4ALDH1A1 | |
| SCHEMBL30749253 | 0.83 | MPO (0.40) | MPOTPOKCNH2CYP3A4MEN1 | |
| SCHEMBL30749262 | 0.83 | MPO (0.50) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30749346 | 0.81 | MPO (0.57) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL27231694 | 0.77 | MPO (0.61) | MPOTPOKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |