Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 6/20 | 0.40 |
| ▸ | TPO | P07202 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749267 | 0.92 | MPO (0.38) | MPOTPOCYP3A4KCNH2ALDH1A1 | |
| SCHEMBL30749309 | 0.90 | ALDH1A1 (0.37) | ALDH1A1MEN1LMNAMAPTTSHR | |
| SCHEMBL30749245 | 0.83 | MPO (0.54) | MPOTPOCYP3A4KCNH2ALDH1A1 | |
| SCHEMBL27224146 | 0.82 | CPT1A (0.34) | ALDH1A1MEN1LMNAKMT2ANPSR1 | |
| SCHEMBL27231643 | 0.82 | CPT1A (0.34) | ALDH1A1MEN1LMNAKMT2ANPSR1 | |
| SCHEMBL30749335 | 0.81 | MEN1 (0.33) | ALDH1A1SMN1; SMN2MEN1LMNAMAPT | |
| SCHEMBL27223609 | 0.76 | MPO (0.56) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27224199 | 0.76 | MPO (0.56) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749376 | 0.74 | MPO (0.51) | MPOTPOCYP3A4KCNH2ALDH1A1 | |
| SCHEMBL27223595 | 0.74 | MPO (0.51) | MPOTPOCYP3A4KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |