Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223619 | 0.95 | IDO1 (0.37) | ALDH1A1ALOX15HPGDHSD17B10IDO1 | |
| SCHEMBL30749256 | 0.95 | IDO1 (0.37) | ALDH1A1ALOX15HPGDHSD17B10IDO1 | |
| SCHEMBL27224134 | 0.90 | ALOX15 (0.38) | ALDH1A1ALOX15HPGDHSD17B10IDO1 | |
| SCHEMBL27223567 | 0.82 | ATM (0.38) | ALOX15IDO1ATMMAPTNPSR1 | |
| SCHEMBL30749339 | 0.82 | JAK2 (0.43) | ALDH1A1ALOX15HPGDIDO1ATM | |
| SCHEMBL27223438 | 0.82 | JAK2 (0.43) | ALDH1A1ALOX15HPGDIDO1ATM | |
| SCHEMBL27224082 | 0.81 | JAK2 (0.46) | ALDH1A1ALOX15HPGDHSD17B10IDO1 | |
| SCHEMBL30749250 | 0.81 | JAK2 (0.46) | ALDH1A1ALOX15HPGDHSD17B10IDO1 | |
| SCHEMBL30749240 | 0.80 | MEN1 (0.40) | ALDH1A1ALOX15HPGDHSD17B10IDO1 | |
| SCHEMBL31556733 | 0.80 | MEN1 (0.40) | ALDH1A1ALOX15HPGDHSD17B10IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |