Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 4/20 | 0.34 |
| ▸ | FNTB | P49356 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556638 | 0.91 | ALDH1A1 (0.41) | ALDH1A1FNTAFNTBMEN1KMT2A | |
| SCHEMBL30749247 | 0.89 | ALDH1A1 (0.40) | ALDH1A1FNTAFNTBMEN1KMT2A | |
| SCHEMBL30749364 | 0.89 | ALDH1A1 (0.40) | ALDH1A1FNTAFNTBMEN1KMT2A | |
| SCHEMBL27224163 | 0.84 | TDP1 (0.36) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL27224212 | 0.84 | TDP1 (0.36) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL27231932 | 0.82 | FDFT1 (0.33) | LMNAMAPTTSHRHTT | |
| SCHEMBL27223580 | 0.82 | FDFT1 (0.33) | LMNAMAPTTSHRHTT | |
| SCHEMBL27224064 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL30749329 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ALMNANPSR1 | |
| SCHEMBL30749316 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |