Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749282 | 0.89 | ALDH1A1 (0.35) | ALDH1A1CNR1NR1H2USP30MEN1 | |
| SCHEMBL31556638 | 0.85 | ALDH1A1 (0.41) | ALDH1A1CNR1USP30MEN1KMT2A | |
| SCHEMBL28896244 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CNR1NR1H2USP30MEN1 | |
| SCHEMBL27231932 | 0.83 | FDFT1 (0.33) | LMNAMAPTTSHRHTTCYP2C9 | |
| SCHEMBL27223580 | 0.83 | FDFT1 (0.33) | LMNAMAPTTSHRHTTCYP2C9 | |
| SCHEMBL30749364 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CNR1USP30MEN1KMT2A | |
| SCHEMBL27223643 | 0.72 | TSHR (0.32) | LMNATSHRHTT | |
| SCHEMBL27231815 | 0.72 | TSHR (0.32) | LMNATSHRHTT | |
| SCHEMBL29932069 | 0.72 | RIPK1 (0.43) | ALDH1A1NR1H2USP30MEN1KMT2A | |
| SCHEMBL38652319 | 0.71 | NR1H2 (0.37) | ALDH1A1NR1H2USP30MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |