Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 17/20 | 0.46 |
| ▸ | TPO | P07202 | 13/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223964 | 1.00 | MPO (0.46) | MPOTPOPARP1PDK1PDK2 | |
| SCHEMBL27224137 | 0.91 | MPO (0.50) | MPOTPO | |
| SCHEMBL27223472 | 0.89 | MPO (0.49) | MPOTPO | |
| SCHEMBL30749340 | 0.89 | MPO (0.49) | MPOTPO | |
| SCHEMBL30749327 | 0.83 | MPO (0.53) | MPOTPO | |
| SCHEMBL30749317 | 0.83 | MPO (0.59) | MPOTPO | |
| SCHEMBL27223477 | 0.83 | MPO (0.59) | MPOTPO | |
| SCHEMBL30749298 | 0.82 | MPO (0.58) | MPOTPO | |
| SCHEMBL27224127 | 0.82 | MPO (0.58) | MPOTPO | |
| SCHEMBL30749360 | 0.82 | MPO (0.59) | MPOTPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |