Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 20/20 | 0.59 |
| ▸ | TPO | P07202 | 16/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223531 | 1.00 | MPO (0.59) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749324 | 0.94 | MPO (0.71) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27223452 | 0.87 | MPO (0.47) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749255 | 0.87 | MPO (0.47) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749340 | 0.85 | MPO (0.49) | MPOTPO | |
| SCHEMBL27223472 | 0.85 | MPO (0.49) | MPOTPO | |
| Trifluoroacetic Acid SCHEMBL30749336 | 0.83 | MPO (0.51) | MPOTPOCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL27223478 | 0.83 | MPO (0.51) | MPOTPOCYP3A4 | |
| SCHEMBL30749367 | 0.82 | MPO (0.46) | MPOTPO | |
| SCHEMBL27223964 | 0.82 | MPO (0.46) | MPOTPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |