Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.73 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.56 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183473 | 1.00 | PARP1 (0.73) | PARP1PBRM1IMPDH2IMPDH1NR4A1 | |
| SCHEMBL30455376 | 1.00 | PARP1 (0.73) | PARP1PBRM1IMPDH2IMPDH1NR4A1 | |
| SCHEMBL10526864 | 0.88 | PBRM1 (0.67) | PARP1PBRM1IMPDH2IMPDH1NR4A1 | |
| SCHEMBL27872217 | 0.87 | IMPDH2 (0.58) | PARP1PBRM1IMPDH2IMPDH1DYRK1A | |
| SCHEMBL6688622 | 0.84 | PARP1 (1.00) | PARP1PBRM1NR4A1NR4A2NR4A3 | |
| SCHEMBL30006934 | 0.84 | IMPDH2 (0.55) | PARP1PBRM1IMPDH2IMPDH1DYRK1A | |
| SCHEMBL28318301 | 0.84 | IMPDH2 (0.55) | PARP1PBRM1IMPDH2IMPDH1DYRK1A | |
| SCHEMBL6007642 | 0.84 | IMPDH2 (0.55) | PARP1PBRM1IMPDH2IMPDH1KDM4E | |
| SCHEMBL6129592 | 0.84 | IMPDH2 (0.55) | PARP1PBRM1IMPDH2IMPDH1DYRK1A | |
| SCHEMBL28260202 | 0.82 | PARP1 (0.55) | PARP1PBRM1KDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425654-A | 2, 8-diazaspiro [4.5] decane compounds | 基因泰克公司 | 2024-01-19 | — | — | CN | disclosed |