Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 4/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749436 | 0.84 | KRAS (0.52) | KRASSOS1PIK3CAMTORROCK1 | |
| SCHEMBL31753865 | 0.82 | HTT (0.45) | KRASSOS1PIK3CAMTORROCK1 | |
| SCHEMBL29882136 | 0.81 | KRAS (0.42) | KRASSOS1ROCK1LMNADHFR | |
| SCHEMBL29926474 | 0.80 | KRAS (0.48) | KRASSOS1PIK3CAMTORROCK1 | |
| SCHEMBL25746374 | 0.80 | KRAS (0.48) | KRASSOS1PIK3CAMTORROCK1 | |
| SCHEMBL21494905 | 0.80 | KRAS (0.48) | KRASSOS1PIK3CAMTORROCK1 | |
| SCHEMBL31391414 | 0.80 | KRAS (0.48) | KRASSOS1PIK3CAMTORROCK1 | |
| SCHEMBL29882247 | 0.79 | NOS3 (0.42) | PIK3CAMTORLMNAPIK3CBGABRP | |
| SCHEMBL29882037 | 0.76 | ADORA1 (0.36) | KRASSOS1PIK3CAMTORLMNA | |
| SCHEMBL3265628 | 0.74 | POLB (0.61) | LMNAPOLBKMT2AGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240084305-A1 | MODULATORS OF CELL PROLIFERATION AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240084305-A1 | MODULATORS OF CELL PROLIFERATION AND USES THEREOF | MKI67, MYC, CCNK | KRAS 4/4885SOS1 1124/4885PIK3CA 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.