Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076914 | 0.88 | TSHR (0.50) | TSHRRAB9ATP53ALDH1A1KDM4E | |
| SCHEMBL3081201 | 0.88 | TSHR (0.46) | TSHRRAB9ANPC1TP53RECQL | |
| SCHEMBL3068944 | 0.86 | RAB9A (0.45) | TSHRRAB9ANPC1TP53RECQL | |
| SCHEMBL3072339 | 0.83 | TSHR (0.47) | TSHRRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL3068041 | 0.81 | TSHR (0.49) | TSHRRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3074288 | 0.80 | TSHR (0.50) | TSHRTP53SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6310768 | 0.78 | NPY5R (0.49) | RAB9ANPC1TP53RECQLNPY5R | |
| SCHEMBL3069214 | 0.77 | NPC1 (0.42) | TSHRRAB9ANPC1TP53RECQL | |
| SCHEMBL3067391 | 0.76 | KMT2A (0.51) | TSHRRAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3071313 | 0.76 | CYP19A1 (0.44) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | claimed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | claimed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | claimed |
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | disclosed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | TSHR 907/4885RAB9A 2019/4885NPC1 1995/4885 |
| US-20100267555-A1 | Fungicidal mixtures II | CBR3, CBR1, NOX3 | TSHR 364/4885RAB9A 2000/4885NPC1 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.