Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 15/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375085 | 1.00 | ROCK2 (0.49) | ROCK2ROCK1ACACBACACAGRM2 | |
| SCHEMBL31614327 | 0.86 | ROCK2 (0.47) | ROCK2ROCK1ACACBACACADYRK1A | |
| SCHEMBL27376908 | 0.86 | ROCK2 (0.47) | ROCK2ROCK1ACACBACACADYRK1A | |
| SCHEMBL30751435 | 0.82 | ROCK2 (0.53) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL31457047 | 0.82 | ROCK2 (0.53) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL27375848 | 0.81 | GRM2 (0.42) | ROCK2ROCK1GRM2DYRK1AL3MBTL1 | |
| SCHEMBL30751378 | 0.81 | GRM2 (0.42) | ROCK2ROCK1GRM2DYRK1AL3MBTL1 | |
| SCHEMBL12791343 | 0.81 | GRM2 (0.46) | GRM2L3MBTL1 | |
| SCHEMBL30751448 | 0.81 | GRM2 (0.43) | GRM2DYRK1AL3MBTL1 | |
| SCHEMBL30751445 | 0.81 | GRM2 (0.41) | GRM2DYRK1AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |