Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 3/20 | 0.48 |
| ▸ | PRKACG | P22612 | 3/20 | 0.48 |
| ▸ | PRKACB | P22694 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751435 | 1.00 | ROCK2 (0.53) | ROCK2ROCK1BRD4CREBBPACACB | |
| SCHEMBL29773324 | 0.86 | BRD4 (0.49) | ROCK2ROCK1BRD4CREBBPACACB | |
| SCHEMBL30504293 | 0.86 | HDAC1 (0.56) | BRD4CREBBP | |
| SCHEMBL18664426 | 0.83 | HDAC1 (0.60) | BRD4CREBBP | |
| SCHEMBL27376908 | 0.82 | ROCK2 (0.47) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL30751397 | 0.82 | ROCK2 (0.49) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL27375085 | 0.82 | ROCK2 (0.49) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL31614327 | 0.82 | ROCK2 (0.47) | ROCK2ROCK1ACACBACACA | |
| SCHEMBL29773322 | 0.82 | BRD4 (0.52) | BRD4CREBBPACACBACACA | |
| SCHEMBL16410240 | 0.82 | BRD4 (0.53) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |