Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.56 |
| ▸ | BTK | Q06187 | 7/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | CAMK1D | Q8IU85 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10169392 | 0.80 | HPGD (0.55) | SYKBTKJAK2LRRK2HPGD | |
| SCHEMBL14067291 | 0.78 | CAMK1D (0.47) | JAK2LRRK2CAMK1D | |
| SCHEMBL18068375 | 0.78 | BTK (0.74) | SYKBTKCAMK1D | |
| SCHEMBL13303605 | 0.77 | SYK (0.61) | SYKBTKHPGDRXFP1LCK | |
| SCHEMBL18068374 | 0.76 | BTK (0.75) | SYKBTKCAMK1D | |
| SCHEMBL14078456 | 0.76 | SYK (0.53) | SYKBTKJAK2LRRK2HPGD | |
| SCHEMBL31673014 | 0.75 | STK17A (0.46) | JAK2CAMK1D | |
| SCHEMBL14077950 | 0.75 | SYK (0.56) | SYKBTKJAK2LRRK2HPGD | |
| SCHEMBL16801858 | 0.74 | BTK (0.75) | BTKLCKJAK3 | |
| Hydrochloric Acid SCHEMBL31673031 | 0.74 | STK17A (0.46) | JAK2CAMK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | 1910 GENETICS INC (US) | 2025-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | TYK2, PDXK, JAK1 | SYK 201/4885BTK 34/4885JAK2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.