Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.53 |
| ▸ | JAK2 | O60674 | 8/20 | 0.46 |
| ▸ | JAK1 | P23458 | 8/20 | 0.46 |
| ▸ | TYK2 | P29597 | 8/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | KIT | P10721 | 3/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751541 | 1.00 | GPR119 (0.53) | GPR119JAK2JAK1TYK2KCNH2 | |
| SCHEMBL30751567 | 0.91 | GPR119 (0.54) | GPR119 | |
| SCHEMBL30751549 | 0.90 | TYK2 (0.47) | GPR119JAK2JAK1TYK2KCNH2 | |
| SCHEMBL30751498 | 0.88 | GPR119 (0.46) | GPR119JAK2JAK1TYK2PDE4D | |
| SCHEMBL30751534 | 0.84 | PTPN11 (0.51) | GPR119JAK2JAK1TYK2KCNH2 | |
| SCHEMBL30751548 | 0.81 | TYK2 (0.46) | GPR119JAK1TYK2KCNH2 | |
| SCHEMBL30751496 | 0.80 | CAMK1D (0.43) | GPR119JAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL31673032 | 0.80 | TYK2 (0.47) | JAK2JAK1TYK2KCNH2KIT | |
| Hydrochloric Acid SCHEMBL30751536 | 0.80 | TYK2 (0.47) | JAK2JAK1TYK2KCNH2KIT | |
| SCHEMBL30751545 | 0.80 | GPR119 (0.46) | GPR119JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | 1910 GENETICS INC (US) | 2025-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | TYK2, PDXK, JAK1 | GPR119 604/4885JAK2 5/4885JAK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.