Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.47 |
| ▸ | JAK1 | P23458 | 18/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31673018 | 0.92 | TYK2 (0.42) | TYK2JAK1CYP2C19 | |
| SCHEMBL30751548 | 0.91 | TYK2 (0.46) | TYK2JAK1CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL30751517 | 0.85 | TYK2 (0.47) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30751564 | 0.85 | TYK2 (0.46) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30751518 | 0.83 | MAPT (0.44) | TYK2JAK1 | |
| SCHEMBL30751572 | 0.83 | GPR119 (0.43) | TYK2JAK1CYP2C19 | |
| SCHEMBL30751563 | 0.83 | GPR119 (0.43) | TYK2JAK1CYP2C19 | |
| SCHEMBL30751557 | 0.81 | TYK2 (0.54) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30751501 | 0.80 | TYK2 (0.53) | TYK2JAK1CYP2C19KCNH2 | |
| SCHEMBL30751558 | 0.80 | TYK2 (0.53) | TYK2JAK1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | 1910 GENETICS INC (US) | 2025-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257051-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS TYK2 INHIBITORS | TYK2, PDXK, JAK1 | TYK2 1/4885JAK1 3/4885CYP2C19 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.