SCHEMBL30751968

SCHEMBL30751968

[2H]C([2H])([2H])c1ccc(-c2ccc(C([2H])([2H])[2H])c(-c3ccccc3)c2)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
CYP2A6 P11509 1/20 0.39
NPC1 O15118 1/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
DYRK1A Q13627 2/20 0.34
P2RX7 Q99572 1/20 0.34
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
LDHA P00338 2/20 0.33
PTGS2 P35354 2/20 0.33
HPGDS O60760 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
PPARG P37231 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19713117 1.00 CYP3A4 (0.39) CYP3A4CYP2A6NPC1HSD17B1HSD17B2
SCHEMBL19725784 0.85 CYP3A4 (0.50) CYP3A4CYP2A6NPC1HSD17B1HSD17B2
SCHEMBL23294052 0.82 LDHA (0.41) NPC1DYRK1ALDHAKDM4EPOLB
SCHEMBL30129684 0.82 LDHA (0.41) NPC1DYRK1ALDHAKDM4EPOLB
SCHEMBL15695148 0.81 CYP3A4 (0.50) CYP3A4CYP2A6CYP11B1CYP11B2CCR1
SCHEMBL29777927 0.81 CYP3A4 (0.50) CYP3A4CYP2A6CYP11B1CYP11B2CCR1
SCHEMBL24088236 0.79 CYP3A4 (0.50) CYP3A4CYP2A6NPC1HSD17B1HSD17B2
SCHEMBL23608096 0.78 CYP11B1 (0.38) CYP3A4CYP11B1CYP11B2
SCHEMBL31681872 0.78 DYRK1A (0.38) NPC1DYRK1ALDHAUSP7MAP4K4
SCHEMBL19713111 0.78 P2RX7 (0.39) CYP3A4CYP2A6NPC1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184710-A Organic electroluminescent material and device 环球展览公司 2024-06-14 CN disclosed
CN-118084983-A Organic electroluminescent material and device 环球展览公司 2024-05-28 CN disclosed
CN-118084982-A Organic electroluminescent material and device 环球展览公司 2024-05-28 CN disclosed
CN-117801024-A Organic electroluminescent material and device 环球展览公司 2024-04-02 CN disclosed
CN-107522747-B Organic electroluminescent material and device 环球展览公司 2024-03-05 CN disclosed
CN-107522748-B Organic electroluminescent material and device 环球展览公司 2024-01-09 CN disclosed