Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751987 | 0.93 | HSD17B10 (0.58) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL5133970 | 0.84 | HSD17B10 (0.50) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL7515266 | 0.83 | HSD17B10 (0.49) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11161743 | 0.83 | HSD17B10 (0.49) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11161739 | 0.83 | HSD17B10 (0.49) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL5967461 | 0.82 | HDAC3 (0.49) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL5599211 | 0.82 | HSD17B10 (0.51) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13326964 | 0.81 | HSD17B10 (0.50) | HSD17B10HTTSMN1; SMN2CCNE2CCNE1 | |
| SCHEMBL28104033 | 0.80 | PTGDR2 (0.49) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL15153201 | 0.79 | ALDH1A1 (0.53) | HSD17B10KMT2AMEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |