Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133970 | 0.95 | HSD17B10 (0.50) | HSD17B10RIPK1PTGDR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11161743 | 0.93 | HSD17B10 (0.49) | HSD17B10RIPK1PTGDR2KDM1AMEN1 | |
| SCHEMBL8553355 | 0.85 | HTR2C (0.53) | HSD17B10RIPK1 | |
| SCHEMBL13326964 | 0.84 | HSD17B10 (0.50) | HSD17B10RIPK1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30752014 | 0.82 | HSD17B10 (0.51) | HSD17B10RIPK1PTGDR2KDM1AMEN1 | |
| SCHEMBL7515266 | 0.79 | HSD17B10 (0.49) | HSD17B10RIPK1ALDH1A1PTGDR2MEN1 | |
| SCHEMBL11161739 | 0.79 | HSD17B10 (0.49) | HSD17B10ALDH1A1PTGDR2KDM1AMEN1 | |
| SCHEMBL5620628 | 0.79 | TYR (0.48) | HSD17B10RIPK1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL30751987 | 0.78 | HSD17B10 (0.58) | HSD17B10RIPK1ALDH1A1KDM1AMEN1 | |
| SCHEMBL28104033 | 0.77 | PTGDR2 (0.49) | HSD17B10ALDH1A1PTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004032-A1 | OXAZOLIDIONES CONTAINING CYCLOBUTANE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |