Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 16/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 11/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752470 | 0.83 | NOTUM (0.36) | F11KLKB1NOTUMKCNH2 | |
| SCHEMBL30752476 | 0.78 | F11 (0.37) | F11KLKB1NOTUM | |
| SCHEMBL29186014 | 0.78 | F11 (0.37) | F11KLKB1NOTUM | |
| SCHEMBL30752477 | 0.74 | F11 (0.41) | F11KLKB1NOTUMKCNH2 | |
| SCHEMBL30995016 | 0.71 | NOTUM (0.41) | F11KLKB1NOTUMKCNH2 | |
| SCHEMBL30995046 | 0.69 | F11 (0.41) | F11KLKB1NOTUMKCNH2 | |
| SCHEMBL30995002 | 0.69 | FLT3 (0.46) | F11KLKB1NOTUMKCNH2MAPK14 | |
| SCHEMBL30622090 | 0.69 | F11 (0.40) | F11KLKB1NOTUMKCNH2CSNK1D | |
| SCHEMBL28360881 | 0.68 | NOTUM (0.39) | F11KLKB1NOTUMKCNH2 | |
| SCHEMBL29589409 | 0.68 | NOTUM (0.39) | F11KLKB1NOTUMKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586284-A | Macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-02-23 | — | — | CN | disclosed |