Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18919414 | 1.00 | HSPA1A (0.47) | HSPA1APABPC1LMNAMAPTHTT | |
| SCHEMBL29713416 | 0.88 | SMN1; SMN2 (0.50) | LMNAMAPTHTTMEN1USP2 | |
| SCHEMBL18919397 | 0.88 | SMN1; SMN2 (0.50) | LMNAMAPTHTTMEN1USP2 | |
| SCHEMBL18942744 | 0.82 | KMT2A (0.38) | HSPA1APABPC1LMNAMAPTHTT | |
| SCHEMBL18919379 | 0.81 | TYMS (0.46) | LMNAMAPTHTTMEN1USP2 | |
| SCHEMBL20574341 | 0.80 | ALDH1A1 (0.46) | LMNAMAPTMEN1KMT2AGAA | |
| SCHEMBL18873218 | 0.78 | HSPA1A (0.56) | HSPA1APABPC1LMNAMAPTHTT | |
| SCHEMBL18919373 | 0.76 | KMT2A (0.41) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| 3,4-Dimethylphenylmaleimide SCHEMBL5074358 | 0.74 | PARP1 (0.53) | HSPA1APABPC1MAPTSMN1; SMN2GAA | |
| SCHEMBL16356262 | 0.74 | HSPA1A (0.49) | HSPA1APABPC1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914240-B | Norbornenone compounds releasing carbon monoxide | 奥塔哥创新有限公司 | 2024-02-20 | — | — | CN | disclosed |