Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 17/20 | 1.00 |
| ▸ | CAMKK1 | Q8N5S9 | 4/20 | 1.00 |
| ▸ | SGK1 | O00141 | 3/20 | 1.00 |
| ▸ | AURKA | O14965 | 1/20 | 1.00 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 1.00 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 1.00 |
| ▸ | AXL | P30530 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gsk-650394 SCHEMBL29368746 | 1.00 | CAMKK2 (1.00) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| Gsk-650394 SCHEMBL3767908 | 1.00 | CAMKK2 (1.00) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL3767383 | 0.81 | CAMKK2 (1.00) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL3768084 | 0.79 | CAMKK2 (1.00) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL3767167 | 0.79 | CAMKK2 (0.76) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL3762417 | 0.78 | CAMKK2 (0.74) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL3764354 | 0.78 | CAMKK2 (0.82) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL3766865 | 0.78 | CAMKK2 (1.00) | CAMKK2CAMKK1SGK1AURKASGK3 | |
| SCHEMBL3774587 | 0.77 | AXL (1.00) | CAMKK2SGK1AURKASGK2AXL | |
| SCHEMBL3759420 | 0.77 | AXL (1.00) | CAMKK2SGK1AURKASGK2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| CN-119950724-A | Application of SGK1 as marker in tumor immunotherapy | 北京大学 | 2025-05-09 | — | — | CN | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-118021814-A | Combination therapy with EHMT2 inhibitors | EPIZYME股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-110621316-B | Combination therapy with EHMT2 inhibitors | EPIZYME股份有限公司 | 2024-01-26 | — | — | CN | disclosed |