Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.78 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333988 | 0.88 | PKM (1.00) | PKMMCOLN3TSHRMAPTLMNA | |
| Hydrochloric Acid SCHEMBL932094 | 0.87 | PKM (0.97) | PKMMCOLN3TSHRMAPTLMNA | |
| SCHEMBL4225535 | 0.85 | ALDH1A1 (0.72) | PKMTSHRMAPTALDH1A1GAA | |
| SCHEMBL6793698 | 0.83 | PKM (0.89) | PKMMCOLN3TSHRLMNASMN1; SMN2 | |
| SCHEMBL13369235 | 0.79 | ALDH1A1 (0.57) | PKMMAPTALDH1A1GAALMNA | |
| Hydrochloric Acid SCHEMBL9780283 | 0.78 | PKM (0.79) | PKMMCOLN3TSHRLMNASMN1; SMN2 | |
| SCHEMBL17246 | 0.78 | MAPT (0.68) | PKMMAPTALDH1A1GAALMNA | |
| SCHEMBL893688 | 0.78 | MAPT (0.68) | PKMMAPTALDH1A1GAALMNA | |
| SCHEMBL6793664 | 0.77 | MAPT (0.63) | PKMTSHRMAPTALDH1A1GAA | |
| SCHEMBL6792483 | 0.77 | PKM (0.73) | PKMMAPTALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720528-A | Oxadiazole sulfonamide compound containing pyrazole structure, and preparation method and application thereof | 贵州大学 | 2024-03-19 | — | — | CN | disclosed |