Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051395 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL15614698 | 0.94 | GAA (0.61) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL12344230 | 0.92 | SMN1; SMN2 (0.48) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL21499883 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL12340054 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL3057044 | 0.88 | MAPT (0.73) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL21499923 | 0.87 | MAPT (0.45) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL22542968 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL30754712 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53MAPTCCR2CCR5 | |
| SCHEMBL26034757 | 0.84 | TP53 (0.53) | SMN1; SMN2TP53MAPTCCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630115-B1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING MITOCHONDRIAL UNCOUPLERS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2025-12-10 | — | — | EP | disclosed |
| US-11896591-B2 | Compositions and methods for preparing and using mitochondrial uncouplers | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2024-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11896591-B2 | Compositions and methods for preparing and using mitochondrial uncouplers | ACAD9, GPR119, NDUFAF1 | SMN1; SMN2 334/4885TP53 3537/4885MAPT 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.