Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 8/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PDE8A | O60658 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372371 | 1.00 | TRPV3 (0.44) | TRPV3HTR1ADRD2DRD4KCNH2 | |
| SCHEMBL4125325 | 0.87 | CCR1 (0.39) | HTR1ADRD2IDO1ADORA2ACNR2 | |
| SCHEMBL30755185 | 0.85 | TRPV3 (0.39) | TRPV3HTR1ADRD2DRD4KCNH2 | |
| SCHEMBL27372375 | 0.85 | TRPV3 (0.39) | TRPV3HTR1ADRD2DRD4KCNH2 | |
| SCHEMBL9937973 | 0.80 | CNR2 (0.42) | HTR1ADRD2ADORA2ACNR2PDE8A | |
| SCHEMBL9938125 | 0.80 | CNR2 (0.45) | TRPV3HTR1ADRD2ADORA2ACNR2 | |
| SCHEMBL20436513 | 0.77 | TRPV3 (0.43) | TRPV3HTR1ADRD2DRD4KCNH2 | |
| SCHEMBL23529956 | 0.76 | MEN1 (0.40) | CNR2 | |
| SCHEMBL29549767 | 0.76 | MEN1 (0.40) | CNR2 | |
| SCHEMBL23529970 | 0.72 | DRD2 (0.42) | HTR1ADRD2DRD4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562016-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |