Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426250 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL13580146 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL10437608 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL10437610 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL10437606 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8430376 | 0.73 | HDAC8 (0.33) | — | |
| SCHEMBL7458765 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL7458769 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL8314886 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL2112085 | 0.68 | SMN1; SMN2 (0.45) | MEN1KMT2AKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7667055-B2 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7550608-B2 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7541458-B2 | β-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7358378-B2 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| EP-1888522-A2 | ß-LACTAM SYNTHESIS | Florida State University Research Foundation, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006135670-A2 | β-LACTAM SYNTHESIS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281932-A1 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281914-A1 | Beta-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | COASY, PARG, PIN4 | ALDH1A1 4039/4885MEN1 179/4885KMT2A 1366/4885 |
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | COASY, PARG, PIN4 | ALDH1A1 4039/4885MEN1 179/4885KMT2A 1366/4885 |
| US-20060281914-A1 | Beta-lactam synthesis | COASY, MANBA, DCXR | ALDH1A1 1215/4885MEN1 100/4885KMT2A 1934/4885 |
| US-20060281932-A1 | Processes for the preparation of docetaxel | PDCD10, PDS5B, DHCR7 | ALDH1A1 954/4885MEN1 1927/4885KMT2A 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.