SCHEMBL30757604

SCHEMBL30757604

FC(F)(F)c1cccc(SCc2c[nH]nn2)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
DAO P14920 1/20 0.41
ALDH1A1 P00352 3/20 0.39
GAA P10253 3/20 0.39
POLB P06746 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ATM Q13315 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NOTUM Q6P988 2/20 0.36
MAPT P10636 2/20 0.36
XBP1 P17861 2/20 0.36
AGTR1 P30556 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17964546 0.77 NPC1 (0.44) DAOALDH1A1GAAPOLBL3MBTL1
SCHEMBL30757701 0.76 MTNR1A (0.44) ALDH1A1MAPTRAB9A
SCHEMBL11172699 0.74 GRM5 (0.48) KDM4EDAOALDH1A1GAAPOLB
Hydrochloric Acid SCHEMBL11163925 0.73 GRM5 (0.47) KDM4EDAOALDH1A1GAAPOLB
SCHEMBL3892638 0.71 ALDH1A1 (0.58) KDM4EDAOALDH1A1GAAPOLB
SCHEMBL23457573 0.71 DAO (0.39) DAOL3MBTL1NOTUMMAPTHPGD
SCHEMBL29699596 0.71 DAO (0.39) DAOL3MBTL1NOTUMMAPTHPGD
SCHEMBL30757660 0.70 IDO1 (0.33) ALDH1A1POLBL3MBTL1NOTUM
SCHEMBL27722503 0.70 KDM4E (0.53) KDM4EDAOALDH1A1GAAPOLB
SCHEMBL17074492 0.69 ATM (0.49) KDM4EALDH1A1GAAPOLBSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543442-A1 TRIAZOLES FOR USE IN THE TREATMENT OF OCULAR DISEASES Miramoon Pharma, S.L. (ES) 2025-04-30 EP claimed
WO-2023247712-A1 TRIAZOLES FOR USE IN THE TREATMENT OF OCULAR DISEASES MIRAMOON PHARMA, S.L. (ES) 2023-12-28 WO claimed
EP-4543442-A1 TRIAZOLES FOR USE IN THE TREATMENT OF OCULAR DISEASES Miramoon Pharma, S.L. (ES) 2025-04-30 EP disclosed
CN-119768168-A Triazole for use in the treatment of ocular diseases 米拉蒙制药有限责任公司 2025-04-04 CN disclosed
WO-2023247712-A1 TRIAZOLES FOR USE IN THE TREATMENT OF OCULAR DISEASES MIRAMOON PHARMA, S.L. (ES) 2023-12-28 WO disclosed