SCHEMBL30758581

SCHEMBL30758581

CCc1ccc(N2C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 6/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
GAA P10253 1/20 0.62
RAB9A P51151 1/20 0.62
KDM4E B2RXH2 1/20 0.59
ALDH1A1 P00352 1/20 0.59
CYP1A2 P05177 1/20 0.59
POLB P06746 1/20 0.59
HPGD P15428 1/20 0.59
CYP2C19 P33261 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MGLL Q99685 1/20 0.58
PPARA Q07869 3/20 0.57
PPARD Q03181 2/20 0.57
NR1H2 P55055 2/20 0.55
PPARG P37231 1/20 0.55
RPS6KA2 Q15349 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13412864 1.00 NR1H3 (0.62) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL25918280 0.95 NR1H3 (0.57) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL25918284 0.90 NR1H3 (0.64) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL9480783 0.84 NR1H3 (0.66) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL4649471 0.83 KMT2A (0.78) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL4594655 0.81 NR1H3 (0.62) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL7329212 0.81 KMT2A (0.63) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL2688855 0.81 NR1H3 (0.62) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL15295106 0.80 NR1H3 (0.71) NR1H3MEN1KMT2AGAARAB9A
SCHEMBL30472945 0.79 ALDH1A1 (0.72) MEN1KMT2AGAARAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466799-B N-substituted phthalic acid diamide preparation method of imine compound 西北师范大学 2024-12-24 CN disclosed
CN-117466799-A Preparation method of N-substituted phthalimide compound 西北师范大学 2024-01-30 CN disclosed