Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | ESRRG | P62508 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | FPR2 | P25090 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.63 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.63 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.63 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335992 | 0.98 | KMT2A (0.71) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL7705937 | 0.93 | ALDH1A1 (0.76) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL15618832 | 0.91 | RAB9A (0.77) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL28489579 | 0.90 | NPC1 (0.72) | KMT2ARAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL16562279 | 0.87 | ALDH1A1 (0.69) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL6570625 | 0.85 | RAB9A (0.70) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL9313096 | 0.85 | MAPT (0.71) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL1569166 | 0.84 | KMT2A (0.72) | KMT2ARAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL3241452 | 0.84 | RAB9A (0.68) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL16562294 | 0.84 | KMT2A (0.70) | KMT2ARAB9AMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466799-B | N-substituted phthalic acid diamide preparation method of imine compound | 西北师范大学 | 2024-12-24 | — | — | CN | disclosed |
| CN-117466799-A | Preparation method of N-substituted phthalimide compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |