SCHEMBL30758604

SCHEMBL30758604

C[C@H](CO)C(N)Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.70
CYP2D6 P10635 1/20 0.61
SLC6A2 P23975 2/20 0.59
TAAR1 Q96RJ0 2/20 0.59
MAOA P21397 1/20 0.59
SLC6A4 P31645 1/20 0.59
SLC6A3 Q01959 1/20 0.59
SIGMAR1 Q99720 1/20 0.59
CYP2A6 P11509 1/20 0.59
ADORA2A P29274 1/20 0.59
ADORA1 P30542 1/20 0.59
EPHX1 P07099 1/20 0.52
CSNK1E P49674 1/20 0.49
ALPI P09923 1/20 0.48
PKM P14618 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48
LAP3 P28838 4/20 0.46
ANPEP P15144 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30758601 1.00 TRPA1 (0.70) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL3619292 0.86 TRPA1 (0.68) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL3619294 0.86 TRPA1 (0.68) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL3844176 0.83 CYP2D6 (0.61) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL28266462 0.83 CYP2D6 (0.61) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL15101101 0.83 TRPA1 (1.00) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL23752456 0.81 SLC6A2 (0.61) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL6193282 0.81 SLC6A2 (0.61) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL2232612 0.81 SLC6A2 (0.61) TRPA1CYP2D6SLC6A2TAAR1MAOA
SCHEMBL6191623 0.81 SLC6A2 (0.61) TRPA1CYP2D6SLC6A2TAAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510547-A Spiro chiral platinum (II) and palladium (II) complex circularly polarized luminescent material and application thereof 浙江工业大学 2024-02-06 CN disclosed