Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | LAP3 | P28838 | 4/20 | 0.51 |
| ▸ | ANPEP | P15144 | 2/20 | 0.51 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.51 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752456 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL8091553 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL29941240 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6191623 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6193282 | 1.00 | SLC6A2 (0.61) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL27535848 | 0.98 | SLC6A2 (0.59) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Bicarbonate SCHEMBL7838533 | 0.94 | SLC15A1 (0.56) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6575399 | 0.83 | SLC6A2 (0.57) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6580061 | 0.83 | SLC6A2 (0.57) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL22431194 | 0.82 | EPHX1 (0.58) | SLC6A2TAAR1MAOASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105152978-B | A kind of preparation method of the butanol of 3 tert-butoxycarbonylamino of (2R, 3S) 1 chlorine, 4 phenyl 2 | 上海应用技术学院 | 2017-08-25 | — | — | CN | claimed |
| US-8829208-B2 | Process for the preparation of darunavir and darunavir intermediates | MAPI PHARMA LTD. (IL) | 2014-09-09 | — | — | US | claimed |
| EP-2528923-B1 | PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES | MAPI PHARMA LTD (IL) | 2014-07-30 | — | — | EP | claimed |
| EP-2528923-A1 | PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES | Mapi Pharma Limited (IL) | 2012-12-05 | — | — | EP | claimed |
| US-20120296101-A1 | PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES | MAPI PHARMA LIMITED (IL) | 2012-11-22 | — | — | US | claimed |
| CN-102725295-A | Process for the preparation of darunavir and darunavir intermediates | MAPI PHARMA HK LTD | 2012-10-10 | — | — | CN | claimed |
| WO-2011092687-A1 | PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES | MAPI PHARMA HK LIMITED (CN) | 2011-08-04 | — | — | WO | claimed |
| US-5936104-A | Process for producing 1,2-epoxy-3-amino-4-phenylbutane derivatives | KANEKA CORPORATION (JP) | 1999-08-10 | — | — | US | claimed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200278346-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ADJACENT ACQUISITION CO., LLC | 2020-09-03 | — | — | US | disclosed |
| US-5559256-A | Aminediol protease inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1996-09-24 | — | — | US | disclosed |
| CN-1085546-A | Aminediol protease inhibitors | SQUIBB & SONS INC (US) | 1994-04-20 | — | — | CN | disclosed |
| US-4983567-A | Immunomodulators and methods of making same | BIOMEASURE, INC. (US) | 1991-01-08 | — | — | US | disclosed |
| US-4871870-A | Immunomodulators and method of making same | BIOMEASURE, INC. (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0283260-A1 | Immunomodulators and method of making same | BIOMEASURE, INC. (US) | 1988-09-21 | — | — | EP | disclosed |
| US-4146560-A | HYDROGENATION; COPPER-COBALT-CHROMIUM CATALYST | TEXACO DEVELOPMENT CORP. (US) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120296101-A1 | PROCESS FOR THE PREPARATION OF DARUNAVIR AND DARUNAVIR INTERMEDIATES | CYP3A43, CYP3A4, DHPS | SLC6A2 4390/4885TAAR1 4509/4885MAOA 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.