Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30922876 | 0.85 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL14533317 | 0.85 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL17075668 | 0.85 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL30407016 | 0.83 | GPR119 (0.49) | HPGDGPR119 | |
| SCHEMBL30662966 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL30663073 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL14368864 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL14368873 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL4424219 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AGLS | |
| SCHEMBL5231864 | 0.83 | MEN1 (0.50) | MEN1ALDH1A1MAPTKMT2AGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573095-A1 | PYRIDOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024040131-A1 | PYRIDOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2024-02-22 | — | — | WO | disclosed |