Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533317 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AACKR3 | |
| SCHEMBL30922876 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AACKR3 | |
| SCHEMBL26213031 | 0.92 | NR1H2 (0.43) | MEN1ALDH1A1MAPTKMT2AACKR3 | |
| SCHEMBL13694467 | 0.92 | NR1H2 (0.43) | MEN1ALDH1A1MAPTKMT2AACKR3 | |
| SCHEMBL14678793 | 0.92 | NR1H2 (0.43) | MEN1ALDH1A1MAPTKMT2AACKR3 | |
| SCHEMBL14282766 | 0.86 | NR1H2 (0.50) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL30759015 | 0.85 | MEN1 (0.45) | MEN1ALDH1A1MAPTKMT2AACKR3 | |
| SCHEMBL13509914 | 0.84 | HPGD (0.47) | HPGDNR1H2EPHX1 | |
| SCHEMBL18309954 | 0.81 | HPGD (0.41) | MEN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL30922937 | 0.80 | MEN1 (0.61) | MEN1ALDH1A1MAPTKMT2AACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570632-B2 | Indole derivatives and uses thereof for treating a cancer | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2026-03-10 | — | — | US | disclosed |
| EP-4175718-B1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIV CLAUDE BERNARD LYON (FR) | 2024-10-02 | — | — | EP | disclosed |
| CN-115843271-B | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2024-08-13 | — | — | CN | disclosed |
| US-20230278983-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2023-09-07 | — | — | US | disclosed |
| US-20230278983-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2023-09-07 | — | — | US | disclosed |
| EP-4175718-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 2023-05-10 | — | — | EP | disclosed |
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | disclosed |
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |
| EP-3053923-B1 | TRIAZOLOPYRAZINE DERIVATIVES AS TYROSIN KINASE INHIBITORS | KOREA RES INST CHEMICAL TECH (KR) | 2018-04-11 | — | — | EP | disclosed |
| EP-3053923-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | Korea Research Institute of Chemical Technology (KR) | 2016-08-10 | — | — | EP | disclosed |
| US-9403831-B2 | Triazolopyrazine derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-08-02 | — | — | US | disclosed |
| US-9403831-B2 | Triazolopyrazine derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-08-02 | — | — | US | disclosed |
| US-9403831-B2 | Triazolopyrazine derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-08-02 | — | — | US | disclosed |
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | HANDOK INC. (KR) | 2015-09-17 | — | — | US | disclosed |
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | HANDOK INC. (KR) | 2015-09-17 | — | — | US | disclosed |
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | HANDOK INC. (KR) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570632-B2 | Indole derivatives and uses thereof for treating a cancer | CKS2, CSNK2A3, CSNK1A1L | MEN1 3609/4885ALDH1A1 1571/4885MAPT 4718/4885 |
| US-20230278983-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | CSNK2A1, IDO1, CSNK2A3 | MEN1 2477/4885ALDH1A1 995/4885MAPT 2556/4885 |
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | MET, RET, BRAF | MEN1 1181/4885ALDH1A1 2687/4885MAPT 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.