Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | LTK | P29376 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | MST1R | Q04912 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18229915 | 1.00 | PDE3B (0.49) | PDE3BPDE3ALTKALKDYRK1B | |
| SCHEMBL7422898 | 0.78 | KDM4E (0.55) | PDE3BPDE3ALTKALKDYRK1B | |
| SCHEMBL2119422 | 0.76 | LTK (0.51) | PDE3BPDE3ALTKALKDYRK1B | |
| SCHEMBL3479430 | 0.75 | LTK (0.41) | PDE3BPDE3ALTKALKDYRK1B | |
| SCHEMBL237635 | 0.75 | PDE3B (0.46) | PDE3BPDE3ALTKALKDYRK1B | |
| SCHEMBL29515639 | 0.75 | MET (0.51) | PDE3BPDE3ALTKALKDYRK1B | |
| Hydrochloric Acid SCHEMBL29737397 | 0.74 | AKT1 (0.50) | PDE3BPDE3ALTKALKDYRK1B | |
| SCHEMBL4243106 | 0.71 | ACVR1 (0.39) | LTKALKDYRK1BRETMET | |
| SCHEMBL4496736 | 0.69 | LTK (0.48) | PDE3BPDE3ALTKALKDYRK1B | |
| SCHEMBL17796160 | 0.68 | PDE3B (0.51) | PDE3BPDE3ALTKALKDYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064402-A1 | METHOD FOR TREATING SICKLE CELL DISEASE BY TARGETING SENESCENT CELLS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2025-03-27 | — | — | WO | disclosed |
| CN-117651700-A | 2-aminobenzothiazole compounds and methods of use | 安进公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117561063-A | Heterocyclic compounds and methods of use | 安进公司 | 2024-02-13 | — | — | CN | disclosed |