SCHEMBL30759539

SCHEMBL30759539

COc1cc2c(cc1Br)-c1c(c(C(=O)N3CCNC(=O)C3(C)C)nn1-c1ccccn1)CC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 2/20 0.39
▸ CDK2 P24941 2/20 0.39
▸ CCNA1 P78396 2/20 0.39
▸ PIK3CD O00329 1/20 0.36
▸ PIK3R2 O00459 1/20 0.36
▸ PIK3CA P42336 1/20 0.36
▸ PIK3CB P42338 1/20 0.36
▸ PIK3CG P48736 1/20 0.36
▸ PIK3R5 Q8WYR1 1/20 0.36
▸ PIK3R3 Q92569 1/20 0.36
▸ KDM4E B2RXH2 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ TSHR P16473 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35
▸ HPGD P15428 1/20 0.35
▸ CYP2C9 P11712 2/20 0.34
▸ CYP2C19 P33261 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ HTR1A P08908 1/20 0.34
▸ DRD4 P21917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27127162 1.00 CCNA2 (0.39) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL27127671 0.90 CNR2 (0.33) PIK3CDMEN1KMT2APDE10ACNR2
SCHEMBL30759572 0.90 CNR2 (0.33) PIK3CDMEN1KMT2APDE10ACNR2
SCHEMBL27127851 0.88 CYP19A1 (0.41) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL30759648 0.85 RAD52 (0.34) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL27127114 0.85 CCNA2 (0.40) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL30759615 0.85 CCNA2 (0.40) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL30759591 0.84 PARP1 (0.31) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL27124910 0.84 PARP1 (0.31) CCNA2CDK2CCNA1PIK3CDPIK3R2
SCHEMBL30759644 0.83 PIK3CD (0.43) CCNA2CDK2CCNA1PIK3CDPIK3R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR CCNA2 2070/4885CDK2 1537/4885CCNA1 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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