SCHEMBL30759648

SCHEMBL30759648

COc1cc2c(cc1Br)-c1c(c(C(=O)N3CCNC(=O)C3(C)C)nn1-c1cc(Cl)cc(Cl)c1)CC2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAD52 P43351 1/20 0.34
▸ PARP1 P09874 1/20 0.34
▸ CNR1 P21554 1/20 0.31
▸ CNR2 P34972 1/20 0.31
▸ F10 P00742 2/20 0.31
▸ CCNA2 P20248 2/20 0.31
▸ CDK2 P24941 2/20 0.31
▸ CCNA1 P78396 2/20 0.31
▸ IKBKB O14920 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ PIK3CD O00329 1/20 0.30
▸ PIK3R2 O00459 1/20 0.30
▸ PIK3CA P42336 1/20 0.30
▸ PIK3CB P42338 1/20 0.30
▸ PIK3CG P48736 1/20 0.30
▸ PIK3R5 Q8WYR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27124910 0.88 PARP1 (0.31) RAD52PARP1CCNA2CDK2CCNA1
SCHEMBL30759591 0.88 PARP1 (0.31) RAD52PARP1CCNA2CDK2CCNA1
SCHEMBL27127390 0.86 CYP11B2 (0.42) RAD52PARP1CCNA2CDK2CCNA1
SCHEMBL30759611 0.86 CYP11B2 (0.42) RAD52PARP1CCNA2CDK2CCNA1
SCHEMBL30759695 0.86 PARP1 (0.36) PARP1CNR1CNR2CCNA2CDK2
SCHEMBL27127515 0.86 PARP1 (0.36) PARP1CNR1CNR2CCNA2CDK2
SCHEMBL30759539 0.85 CCNA2 (0.39) CNR2CCNA2CDK2CCNA1KDM4E
SCHEMBL27127162 0.85 CCNA2 (0.39) CNR2CCNA2CDK2CCNA1KDM4E
SCHEMBL27120380 0.85 CYP11B2 (0.32) RAD52PARP1CCNA2CDK2CCNA1
SCHEMBL30759572 0.84 CNR2 (0.33) PARP1CNR2MEN1KMT2APIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR RAD52 3591/4885PARP1 3837/4885CNR1 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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