SCHEMBL30759553

SCHEMBL30759553

COc1cc2c(cc1-c1cncc(C(N)=O)c1)-c1c(c(C(=O)O)nn1-c1cc(Cl)cc(Cl)c1)CC2

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 4/20 0.38
▸ CDK2 P24941 4/20 0.38
▸ CCNA1 P78396 4/20 0.38
▸ IKBKB O14920 12/20 0.37
▸ RAD52 P43351 1/20 0.36
▸ CYP11B1 P15538 1/20 0.34
▸ CYP11B2 P19099 1/20 0.34
▸ MKNK1 Q9BUB5 1/20 0.34
▸ MKNK2 Q9HBH9 1/20 0.34
▸ ALPL P05186 1/20 0.33
▸ CHUK O15111 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27119960 1.00 CCNA2 (0.38) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL27122870 0.91 RAD52 (0.36) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL30759674 0.90 CCNA2 (0.42) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL27122153 0.90 RAD52 (0.40) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL27122184 0.90 IKBKB (0.36) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL27120495 0.90 CCNA2 (0.42) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL27119776 0.89 PDE7A (0.36) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL30759625 0.89 PDE7A (0.36) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL27122174 0.88 RAD52 (0.36) CCNA2CDK2CCNA1IKBKBRAD52
SCHEMBL27120632 0.88 RAD52 (0.39) CCNA2CDK2CCNA1IKBKBRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF GEDEON RICHTER PLC (HU) 2026-01-08 — — US disclosed
EP-4577206-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF Celmatix Inc. (US) 2025-07-02 — — EP disclosed
WO-2024044778-A2 NOVEL MODULATORS OF FSHR AND USES THEREOF CELMATIX INC. (US) 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008783-A1 MODULATORS OF FSHR AND USES THEREOF FSHR, GNRHR, LHCGR CCNA2 2070/4885CDK2 1537/4885CCNA1 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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